Join Dr. Manuel de Lera Ruiz for "Understanding the Essential Requirements for Molecules to Qualify as Drugs using as Case Study The Invention of Antimalarial MK-7602."
Malaria is a devastating disease that affects over half a million people each year mostly children under five years old and pregnant women. Antimalarial drug discovery by and large is focused on the identification of novel drugs to treat and prevent the disease due to the emergence and spread of Plasmodium strains resistant to existing medicines. The Merck Research Labs (led by Dr. David Olsen) and the Walter and Eliza Hall Institute of Medical Research (WEHI) (led by Prof. Alan Cowman), have teamed up to invent novel drug candidates by targeting the Plasmodium parasite via newly identified essential aspartyl proteases.
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