Ashlee M. Plummer-Medeiros
Department/Subdepartment
Education
B.S. Chemistry, North Carolina State University
Ph.D. Molecular Biophysics, Johns Hopkins University
Postdoctoral Fellowship, Harvard Medical School
Areas of Focus
Biological Chemistry
Biography
Research Program
The Plummer lab concentrates on the functional, computational, and structural characterization of bacterial membrane proteins which play a role in the widespread virulence of bacteria. Cell membranes are amazingly complex mixtures of phospholipids and membrane proteins – these membranes surround cells and create a protective barrier against outside threats. The proteins that reside within membranes work in many critically important processes and the dysfunction of these proteins is linked to innumerable diseases, including atherosclerosis, cancer, and neurodegenerative disorders. Our work combines several different experimental techniques, including in vitro biochemical assays, structural biology-based studies, cell-based assays, and computational simulations to understand 1) how these proteins work and 2) how they interact with the surrounding lipid bilayer.
Teaching and Course Information
Fall 2022
- General Chemistry 1 (CHEM 103)
- Research Methodology in Chemistry (CHEM 251)