Publications

Miller, B.R. and Kung, Y. (2018) Structural insight into substrate and product binding in an archaeal mevalonate kinase. PLoS ONE. 13(12): e0208419. Link.

Ragwan, E.R., Arai, E., and Kung, Y. (2018) New crystallographic snapshots of large domain movements in bacterial HMG-CoA reductase. Biochemistry. 57, 5715-5725. Link.

Miller, B.R. and Kung, Y. (2018) Structural features and domain movements controlling substrate binding and cofactor specificity in class II HMG-CoA reductase. Biochemistry. 57, 654-662. Link.

Kung, Y. and Drennan, C.L. (2017) "One-Carbon Chemistry of Nickel-Containing Carbon Monoxide Dehydrogenase and Acetyl-CoA Synthase" in The Biological Chemistry of Nickel. Eds. Deborah Zamble, Magdalena Rowińska-Żyrek, Henryk Kozlowski. London: Royal Society of Chemistry. pp. 121-148. Link.

Dowling, D.P., Kung, Y., Croft, A.K., Taghizadeh, K., Kelly, W.L., Walsh, C.T., and Drennan, C.L. (2016) Structural elements of an NRPS cyclization domain and its intermodule docking domain. Proc. Natl. Acad. Sci. U.S.A. 113, 12432-12437. Link.

Kung, Y., McAndrew, R.P., Xie, X., Liu, C.C., Pereira, J.H., Adams, P.D., and Keasling, J.D. (2014) Constructing tailored isoprenoid products by structure-guided modification of geranylgeranyl reductase. Structure. 22, 1028-1036. Link.

Kung, Y., Runguphan, W., and Keasling, J.D. (2012) From fields to fuels: Recent advances in the microbial production of biofuels. ACS Synth. Biol. 1, 498-513. Link.

Kung, Y., Ando, N., Doukov, T.I., Blasiak, L.C., Seravalli, J., Bender, G., Ragsdale, S.W., and Drennan, C.L. (2012) Visualizing molecular juggling within a B₁₂-dependent methyltransferase complex. Nature. 48, 265-269. Link.

Ando, N., Kung, Y., Can, M., Bender, G., Ragsdale, S.W., and Drennan, C.L. (2012) Transient B₁₂-dependent methyltransferase complexes revealed by small-angle X-ray scattering. J. Am. Chem. Soc. 134, 17945-17954. Link.

Ragsdale, S.W., Li, Y., Bender, G., Gupta, N., Kung, Y., Yan, L., Stich, T.A., Doukov, T.I., Leichert, L., Jenkins, P.M., Bianchetti, C.M., George, S.J., Cramer, S.P., Britt, R.D., Jakob, U., Martens, J.R., Phillips, G.N., and Drennan, C.L. (2012) Redox, haem and CO in enzymatic catalysis and regulation. Biochem. Soc. Trans. 40, 501-507. Link.

Kung, Y. and Drennan, C.L. (2011) A role for nickel-iron cofactors in biological carbon monoxide and carbon dioxide utilization. Curr. Opin. Chem. Biol. 15, 276-283. Link.

Kung, Y., Doukov, T.I., Seravalli, J., Ragsdale, S.W., and Drennan, C.L. (2009) Crystallographic snapshots of cyanide- and water-bound C-clusters from bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase. Biochemistry. 48, 7432-7440. Link.

Mailing Address
Yan Kung
Department of Chemistry, Bryn Mawr College
Bryn Mawr
Pennsylvania, 19010
610-526-5460
Fax: 610-526-5086
ykung@brynmawr.edu

Laboratory: Park Science Building, Room 282

Office: Park Science Building, Room 286